Review



recombinant human integrins αvβ1, αvβ5 αvβ6  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 90
      Buy from Supplier

    Structured Review

    R&D Systems recombinant human integrins αvβ1, αvβ5 αvβ6
    Recombinant Human Integrins αvβ1, αvβ5 αvβ6, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+integrin+%CE%B1v%CE%B26/recombinant+human+%CE%B1v%CE%B26+integrin/pm38641066-206-6-9
    Average 90 stars, based on 1 article reviews
    recombinant human integrins αvβ1, αvβ5 αvβ6 - by Bioz Stars, 2026-10
    90/100 stars

    Images

    Related Articles

    Recombinant:

    Article Title: Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists
    Article Snippet: Solid Phase Receptor Assay (SPRA) for αvβ6 Function Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 1 mM MnCl2) was added to wells (50 μL/well) of a 96-well half-well transparent microtiter plate (Greiner 675061) and incubated overnight at 4° C. Wells were washed 3 times with 150 μL TBS+, and 150 μL of blocking buffer (TBS+ with 1% bovine serum albumin, Sigma A7906) were added. .. Recombinant human integrin αvβ6 (R&D Systems, 3817-AV) was diluted to 0.1 g/mL in TBS+/0.1% bovine serum albumin. .. Recombinant human integrin αvβ6 (R&D Systems, 3817-AV) was diluted to 0.1 g/mL in TBS+/0.1% bovine serum albumin.

    Article Title: Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists
    Article Snippet: Solid Phase Receptor Assay (SPRA) for αvβ6 Function Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, 1 mM MnCl2) was added to wells (50 μL/well) of a 96-well half-well transparent microtiter plate (Greiner 675061) and incubated overnight at 4° C. Wells were washed 3 times with 150 μL TBS+, and 150 μL of blocking buffer (TBS+ with 1% bovine serum albumin, Sigma A7906) were added. .. Recombinant human integrin αvβ6 (R&D Systems, 3817-AV) was diluted to 0.1 μg/mL in TBS+/0.1% bovine serum albumin. .. Recombinant human integrin αvβ6 (R&D Systems, 3817-AV) was diluted to 0.1 μg/mL in TBS+/0.1% bovine serum albumin.

    Article Title: Beta amino acid derivatives as integrin antagonists
    Article Snippet: Recombinant human integrin αvβ6 (R&D Systems, 3817-AV) was diluted to 0.1 μg/mL in TBS+/0.1% bovine serum albumin. .. Recombinant human integrin αvβ6 (R&D Systems, 3817-AV) was diluted to 0.1 μg/mL in TBS+/0.1% bovine serum albumin. ..



    Similar Products

    recombinant human integrin αvβ6 or αvβ8 headpieces  (Thermo Fisher)
    90
    Thermo Fisher recombinant human integrin αvβ6 or αvβ8 headpieces
    Recombinant Human Integrin αvβ6 Or αvβ8 Headpieces, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+integrin+%CE%B1v%CE%B26/pm37704610-423-5-36
    Average 90 stars, based on 1 article reviews
    recombinant human integrin αvβ6 or αvβ8 headpieces - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    human recombinant integrin αvβ6 protein it6-h52e1  (ACROBiosystems)
    90
    ACROBiosystems human recombinant integrin αvβ6 protein it6-h52e1
    Human Recombinant Integrin αvβ6 Protein It6 H52e1, supplied by ACROBiosystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+integrin+%CE%B1v%CE%B26/human+recombinant+integrin+avb6+protein/pmc11803832__mmc1-5-5-10
    Average 90 stars, based on 1 article reviews
    human recombinant integrin αvβ6 protein it6-h52e1 - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    recombinant human integrins αvβ1, αvβ5 αvβ6  (R&D Systems)
    90
    R&D Systems recombinant human integrins αvβ1, αvβ5 αvβ6
    Recombinant Human Integrins αvβ1, αvβ5 αvβ6, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+integrin+%CE%B1v%CE%B26/recombinant+human+%CE%B1v%CE%B26+integrin/pm38641066-206-6-9
    Average 90 stars, based on 1 article reviews
    recombinant human integrins αvβ1, αvβ5 αvβ6 - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    recombinant human αvβ6 integrin  (R&D Systems)
    93
    R&D Systems recombinant human αvβ6 integrin
    Recombinant Human αvβ6 Integrin, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+integrin+%CE%B1v%CE%B26/Recombinant+Human+Integrin+alpha+V+beta+6+Protein%2C+CF/us11884661-1788-16-20
    Average 93 stars, based on 1 article reviews
    recombinant human αvβ6 integrin - by Bioz Stars, 2026-10
    93/100 stars
    		  Buy from Supplier
    recombinant human integrins αvβ1, αvβs αvβ6  (R&D Systems)
    90
    R&D Systems recombinant human integrins αvβ1, αvβs αvβ6
    Soluble galectin-3 (sequential injections, 19.5 - 5000 nM) binding to glycosylated or deglycosylated αv integrins: (A) αvβ1, (B) αvβS and (C) <t>αvβ6</t> immobilised on the surface of a Series S sensor chip CM5 (approximately 1000 RU). (D) Soluble galectin-3 (sequential injections, 156.3-20000 nM) binding to glycosylated or deglycosylated TGFβRII immobilised to a Series S sensor chip CMS (approximately 400 RU). SPR signals were measured in RU and all sensorgrams baseline-corrected. Binding response values plotted in GraphPad Prism with connecting line/curve shown.
    Recombinant Human Integrins αvβ1, αvβs αvβ6, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+integrin+%CE%B1v%CE%B26/recombinant+human+%CE%B1v%CE%B26+integrin/bio_rxiv__2023__10__11__561855-172-8-9
    Average 90 stars, based on 1 article reviews
    recombinant human integrins αvβ1, αvβs αvβ6 - by Bioz Stars, 2026-10
    90/100 stars
    		  Buy from Supplier
    αvβ6  (R&D Systems)
    93
    R&D Systems αvβ6
    Figure 3. Recombinant human integrins αvβ3 and <t>αvβ6,</t> but not α5β1, bind to immobilized S1-RBD. Representative kinetic data for αvβ3 (A and D), αvβ6 (B and E), or α5β1 (C and F) binding to immobilized S1-RBD (A–C), FNIII10 (D–E), or FNIII8-10 (F). Data are presented as representative traces (bold colored lines) collected from one of two (α5β1, 100–1000 nM) or three (αvβ3, 5–450 nM and αvβ6, 5–500 nM) experiments and corresponding 1:1 binding fits (black lines).
    αvβ6, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/recombinant+human+integrin+%CE%B1v%CE%B26/Recombinant+Human+Integrin+alpha+V+beta+6+Protein%2C+CF/pm36669646-200-5-13
    Average 93 stars, based on 1 article reviews
    αvβ6 - by Bioz Stars, 2026-10
    93/100 stars
    		  Buy from Supplier

    Image Search Results


    Soluble galectin-3 (sequential injections, 19.5 - 5000 nM) binding to glycosylated or deglycosylated αv integrins: (A) αvβ1, (B) αvβS and (C) αvβ6 immobilised on the surface of a Series S sensor chip CM5 (approximately 1000 RU). (D) Soluble galectin-3 (sequential injections, 156.3-20000 nM) binding to glycosylated or deglycosylated TGFβRII immobilised to a Series S sensor chip CMS (approximately 400 RU). SPR signals were measured in RU and all sensorgrams baseline-corrected. Binding response values plotted in GraphPad Prism with connecting line/curve shown.

    Journal: bioRxiv

    Article Title: Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis

    doi: 10.1101/2023.10.11.561855

    Figure Lengend Snippet: Soluble galectin-3 (sequential injections, 19.5 - 5000 nM) binding to glycosylated or deglycosylated αv integrins: (A) αvβ1, (B) αvβS and (C) αvβ6 immobilised on the surface of a Series S sensor chip CM5 (approximately 1000 RU). (D) Soluble galectin-3 (sequential injections, 156.3-20000 nM) binding to glycosylated or deglycosylated TGFβRII immobilised to a Series S sensor chip CMS (approximately 400 RU). SPR signals were measured in RU and all sensorgrams baseline-corrected. Binding response values plotted in GraphPad Prism with connecting line/curve shown.

    Article Snippet: Commercially available recombinant human integrins αvβ1, αvβS and αvβ6 (R&D Systems) or TGF beta receptor II protein (Abcam) were diluted in 10 mM sodium acetate pH 4.0 immobilisation buffer and immobilised onto a Series S Sensor Chip CM5 (Cytiva) via the standard amine coupling protocol.

    Techniques: Binding Assay

    Solution competition binding assays performed with the galectin-3 inhibitor GB0139 (blue) or GB1107 (black) for αv integrins: (A) αvβ1, (B) αvβS and (C) αvβ6 or (D) TGFβRII in the presence of galectin-3 at 625 nM. Response values are normalised with respect to the highest binding response (DMSO control) and competitive inhibition graphs plotted in GraphPad Prism. IC50 values were calculated by non-linear regression analysis (binding saturation) - specific binding with hill slope.

    Journal: bioRxiv

    Article Title: Defining the mechanism of galectin-3-mediated TGF-β1 activation and its role in lung fibrosis

    doi: 10.1101/2023.10.11.561855

    Figure Lengend Snippet: Solution competition binding assays performed with the galectin-3 inhibitor GB0139 (blue) or GB1107 (black) for αv integrins: (A) αvβ1, (B) αvβS and (C) αvβ6 or (D) TGFβRII in the presence of galectin-3 at 625 nM. Response values are normalised with respect to the highest binding response (DMSO control) and competitive inhibition graphs plotted in GraphPad Prism. IC50 values were calculated by non-linear regression analysis (binding saturation) - specific binding with hill slope.

    Article Snippet: Commercially available recombinant human integrins αvβ1, αvβS and αvβ6 (R&D Systems) or TGF beta receptor II protein (Abcam) were diluted in 10 mM sodium acetate pH 4.0 immobilisation buffer and immobilised onto a Series S Sensor Chip CM5 (Cytiva) via the standard amine coupling protocol.

    Techniques: Binding Assay, Inhibition

    Figure 3. Recombinant human integrins αvβ3 and αvβ6, but not α5β1, bind to immobilized S1-RBD. Representative kinetic data for αvβ3 (A and D), αvβ6 (B and E), or α5β1 (C and F) binding to immobilized S1-RBD (A–C), FNIII10 (D–E), or FNIII8-10 (F). Data are presented as representative traces (bold colored lines) collected from one of two (α5β1, 100–1000 nM) or three (αvβ3, 5–450 nM and αvβ6, 5–500 nM) experiments and corresponding 1:1 binding fits (black lines).

    Journal: The Journal of biological chemistry

    Article Title: Receptor-binding domain of SARS-CoV-2 is a functional αv-integrin agonist.

    doi: 10.1016/j.jbc.2023.102922

    Figure Lengend Snippet: Figure 3. Recombinant human integrins αvβ3 and αvβ6, but not α5β1, bind to immobilized S1-RBD. Representative kinetic data for αvβ3 (A and D), αvβ6 (B and E), or α5β1 (C and F) binding to immobilized S1-RBD (A–C), FNIII10 (D–E), or FNIII8-10 (F). Data are presented as representative traces (bold colored lines) collected from one of two (α5β1, 100–1000 nM) or three (αvβ3, 5–450 nM and αvβ6, 5–500 nM) experiments and corresponding 1:1 binding fits (black lines).

    Article Snippet: Recombinant human integrins αvβ3 (3050-AV), αvβ6 (3817- AV), and α5β1 (3230-A5) were from R&D Systems.

    Techniques: Recombinant, Binding Assay